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Structure of 58530-47-5
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2-(Pyridin-4-yloxy)acetic acid features a pyridin-4-yloxy moiety linked to a carboxylic acid group, enabling direct integration into bioconjugation workflows. The electron-deficient pyridine ring enhances reactivity in nucleophilic substitution, while the pendant acid facilitates derivatization under standard coupling conditions. This structure offers improved solubility and stability compared to analogous aryl ethers.
2-(Pyridin-4-yloxy)acetic acid serves as a versatile building block for constructing bioactive heterocyclic architectures, particularly in medicinal chemistry and agrochemical development. Its pyridin-4-yloxy functionality enables robust coupling reactions with amines and nucleophiles under mild conditions, while the carboxylic acid group facilitates derivatization via esterification or amide formation. The compound exhibits excellent bench stability and is readily purified by recrystallization, making it well-suited for high-throughput synthesis and process-scale applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: