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Structure of 58534-94-4
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1-Bromo-2-fluoro-3-nitrobenzene features a trifunctional aromatic core enabling precise molecular assembly in cross-coupling and electrophilic substitution workflows. The ortho-halogen arrangement facilitates selective metalation, while the nitro group enhances reactivity in nucleophilic aromatic substitution. This bench-stable compound integrates readily into complex heterocyclic scaffolds under standard conditions.
1-Bromo-2-fluoro-3-nitrobenzene serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling palladium-catalyzed cross-coupling reactions due to its orthogonal reactivity profile. The bromo group facilitates efficient coupling under standard conditions, while the fluoro and nitro substituents provide electronic modulation and enhanced metabolic stability. Its bench-stable nature and compatibility with diverse functional groups make it ideal for sequential functionalization strategies in complex molecule assembly.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: