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Structure of 5860-95-7
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1-(2-Chlorophenyl)-2,2,2-trifluoroethan-1-one features a trifluoromethyl ketone group flanked by an electron-deficient 2-chlorophenyl ring, enabling efficient electrophilic reactivity in C–C bond-forming transformations. This bench-stable compound integrates readily into synthetic sequences requiring strong polarization at the carbonyl center.
1-(2-Chlorophenyl)-2,2,2-trifluoroethan-1-one serves as a versatile building block in medicinal chemistry, enabling efficient construction of fluorinated aryl ketones. Its trifluoromethyl group enhances metabolic stability and lipophilicity, while the ortho-chloro substituent facilitates downstream functionalization via palladium-catalyzed cross-coupling. The compound exhibits good bench stability and is compatible with standard purification methods, making it well-suited for iterative synthesis workflows in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: