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Structure of 58755-70-7
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1-Iodo-4-methoxy-2-nitrobenzene features a reactive iodide handle paired with electron-withdrawing nitro and electron-donating methoxy groups, enabling efficient palladium-catalyzed cross-coupling. This ortho-substituted aryl iodide delivers high functional group tolerance and predictable reactivity in complex molecule assembly.
1-Iodo-4-methoxy-2-nitrobenzene serves as a versatile aryl halide building block for palladium-catalyzed cross-coupling reactions, enabling efficient construction of biaryl and heteroaryl scaffolds. The methoxy group provides moderate electron donation, while the nitro functionality offers orthogonal reactivity for subsequent reduction or nucleophilic substitution. Its stability under standard handling conditions and compatibility with diverse coupling partners make it well-suited for iterative synthesis in medicinal chemistry and materials development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: