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Structure of 588688-45-3
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7-Chloro-1H-indole-4-carboxylic acid features a chlorinated indole scaffold with a carboxylic acid group at the 4-position, enabling direct conjugation in peptide and heterocyclic synthesis. This bench-stable derivative integrates readily into bioactive molecule frameworks, offering enhanced solubility and metabolic stability compared to non-halogenated analogs.
7-Chloro-1H-indole-4-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling direct incorporation into bioactive heterocycles via standard coupling reactions. Its chlorinated indole core offers enhanced metabolic stability and modulates electronic properties for targeted receptor interactions. The carboxylic acid functionality facilitates amide formation, esterification, and transition metal-catalyzed cross-couplings, supporting efficient synthesis of complex scaffolds under routine laboratory conditions. Bench-stable and readily purified by recrystallization, it functions as a reliable intermediate in API development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: