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Structure of 58884-35-8
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4-(6-Methyl-1,2,4,5-tetrazin-3-yl)phenol features a tetrazine core functionalized with a methyl group and a phenolic hydroxyl, enabling efficient bioorthogonal conjugation. The electron-deficient tetrazine engages in rapid inverse electron-demand Diels-Alder reactions with strained dienophiles. This bench-stable compound integrates seamlessly into probe design for live-cell labeling and protein modification workflows.
4-(6-Methyl-1,2,4,5-tetrazin-3-yl)phenol serves as a versatile building block for the synthesis of bioactive heterocycles, leveraging the high reactivity of the tetrazine ring in inverse electron-demand Diels-Alder reactions. Its phenolic functionality enables straightforward derivatization and facilitates purification via crystallization or chromatography. The molecule exhibits excellent bench stability and functional group tolerance, making it well-suited for iterative synthetic campaigns in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H312-H332
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501
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Lot numbers can be found on the outside label of a product: