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Structure of 58914-35-5
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2-Hydroxy-6-(trifluoromethyl)benzaldehyde features a strategically positioned trifluoromethyl group that enhances electron deficiency and metabolic stability. The ortho-hydroxyl moiety enables chelation and facilitates coordination in catalytic systems. This combination delivers enhanced reactivity in transition metal-catalyzed couplings and serves as a key building block in the synthesis of bioactive heterocycles.
2-Hydroxy-6-(trifluoromethyl)benzaldehyde serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient access to substituted benzofuran and benzothiophene scaffolds. Its ortho-hydroxyl group facilitates cyclization reactions, while the electron-withdrawing trifluoromethyl and aldehyde functionalities offer enhanced reactivity in nucleophilic additions and condensation processes. The compound exhibits good bench stability and is readily purified by crystallization, supporting scalable applications in target-oriented synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: