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CS-W001157 4
Total: USD 88.00

2-Benzoxazolinone

  • CAS No. 59-49-4

  • Cat. No. CS-W016534
  • Purity≥96%
  • MDL No.MFCD00005716
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2-Benzoxazolinone|CS-W016534

Structure of 59-49-4

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Description

2-Benzoxazolinone features a fused heterocyclic core combining benzene and oxazolinone rings, offering enhanced stability and predictable reactivity. This scaffold serves as a key building block in medicinal chemistry, enabling direct incorporation into bioactive molecules through selective functionalization at the C-5 position. Its electron-deficient nature facilitates efficient coupling reactions under mild conditions.

Application

2-Benzoxazolinone serves as a versatile building block in synthetic organic chemistry, enabling efficient access to bioactive heterocycles and pharmaceutical intermediates. Its electrophilic carbonyl moiety facilitates nucleophilic addition reactions, while the fused ring system provides structural rigidity and metabolic stability. The compound exhibits excellent bench stability, tolerates diverse functional groups, and simplifies purification—making it ideal for iterative synthesis workflows in medicinal chemistry and process development.

General Information

  • CAS No. 59-49-4
  • Cat. No. CS-W016534
  • Purity ≥96%
  • MDL No. MFCD00005716
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₅NO₂
  • Molecular Weight None
  • Synonym(s) 2-Benzoxazolone; 1,3-Benzoxazol-2(3H)-one; 2-Hydroxybenzoxazole
  • SMILES O=C1OC2=CC=CC=C2N1

Computational Chemistry Data

  • TPSA   46
  • LogP   1.1211
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302+H312+H332
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501

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