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Structure of 5905-69-1
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1-Bromo-4-(difluoromethoxy)benzene features a para-substituted aryl bromide with a difluoromethoxy group enhancing electron-withdrawal and metabolic stability. This bench-stable, moisture-tolerant reagent integrates readily into cross-coupling reactions, enabling efficient access to fluorinated aromatic scaffolds for medicinal chemistry and materials science applications.
1-Bromo-4-(difluoromethoxy)benzene serves as a versatile aryl halide building block for palladium-catalyzed cross-coupling reactions, enabling efficient construction of biaryl architectures. The difluoromethoxy group imparts enhanced metabolic stability and modulates electronic properties, making this compound valuable in medicinal chemistry and agrochemical research. Bench-stable and compatible with standard reaction conditions, it facilitates straightforward functionalization and purification in multi-step syntheses.
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GHS Pictogram :
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GHS No : GHS02
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Signal Word : Danger
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UN#: 1993
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Class : 3
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Packing Group : Ⅲ
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Hazard Statements : H226
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Precautionary Statements : P210-P233-P240-P241-P242-P243-P280-P370+P378-P501
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Lot numbers can be found on the outside label of a product: