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CS-W001157 4
Total: USD 88.00

Di(N-succinimidyl)adipate

  • CAS No. 59156-70-6

  • Cat. No. CS-0115767
  • Purity≥95%
  • MDL No.MFCD01318516

*For research and further manufacturing use only, not for direct human use.

Di(N-succinimidyl)adipate|CS-0115767

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General Information

  • CAS No. 59156-70-6
  • Cat. No. CS-0115767
  • Purity ≥95%
  • MDL No. MFCD01318516
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₁₆N₂O₈
  • Molecular Weight 340.29
  • Synonym(s) None
  • SMILES O=C(ON1C(CCC1=O)=O)CCCCC(ON2C(CCC2=O)=O)=O

Description

Di(N-succinimidyl)adipate is a bifunctional crosslinker featuring two reactive N-hydroxysuccinimide esters. It enables efficient conjugation to primary amines under mild aqueous conditions, facilitating stable amide bond formation in protein labeling and biomaterial engineering.

Application

Di(N-succinimidyl)adipate serves as a bifunctional crosslinking agent, enabling efficient conjugation of primary amines in proteins, peptides, and biomolecules. Its adipoyl spacer provides optimal flexibility and stability, while the N-hydroxysuccinimide (NHS) esters offer high reactivity under physiological conditions. The reagent facilitates site-specific labeling and immobilization with minimal aggregation, making it ideal for bioconjugation workflows requiring precise control and scalable synthesis.

Synthesis

  • Route1

    References

    • Mishra, Narendra Kumar; Joshi, Khashti Ballabh; Verma, Sandeep Molecular Pharmaceutics, 2013 , vol. 10, # 10 p. 3903 - 3912

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

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Computational Chemistry Data

  • TPSA   127.36
  • LogP   -0.2388
  • H_Acceptors   8
  • H_Donors   0
  • Rotatable_Bonds   7

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