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CS-W001157 4
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5-Hydroxy-1,2,3,3-tetramethyl-3H-indol-1-ium iodide

  • CAS No. 59223-23-3

  • Cat. No. CS-0187149
  • Purity≥97%
  • MDL No.None
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

5-Hydroxy-1,2,3,3-tetramethyl-3H-indol-1-ium iodide|CS-0187149

Structure of 59223-23-3

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Description

This tetramethylindolium salt features a hydroxylated indole core with a quaternary nitrogen, delivering enhanced solubility and stability under standard conditions. The iodide counterion ensures high ionic mobility, enabling efficient use in electrochemical studies and as a synthetic precursor for functionalized heterocycles.

Application

5-Hydroxy-1,2,3,3-tetramethyl-3H-indol-1-ium iodide serves as a stable, bench-ready building block for indole-based heterocyclic synthesis. Its quaternary nitrogen center enables straightforward functionalization and facilitates coupling reactions under mild conditions. The molecule exhibits good solubility in polar solvents and tolerance to common protecting group manipulations, making it well-suited for iterative synthesis of complex indole scaffolds in medicinal chemistry and natural product derivatization workflows.

General Information

  • CAS No. 59223-23-3
  • Cat. No. CS-0187149
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, stored under nitrogen, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₆INO
  • Molecular Weight 317.17
  • Synonym(s) 5-hydroxy-1,2,3,3-tetraMethyl-3H-indoliuM iodide
  • SMILES [I-].OC=1C=CC2=C(C1)C(C(=[N+]2C)C)(C)C

Computational Chemistry Data

  • TPSA   23.24
  • LogP   -0.5779
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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