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Structure of 59288-43-6
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5-Hydroxy-6-nitronicotinic acid features a pyridine core bearing both hydroxyl and nitro substituents at adjacent positions, enabling strong hydrogen bonding and enhanced polarity. This combination delivers high solubility in polar solvents and facilitates integration into complex synthetic pathways requiring directional reactivity. The molecule’s stability under standard conditions supports reliable handling in medicinal chemistry applications.
5-Hydroxy-6-nitronicotinic acid serves as a versatile building block for heterocyclic synthesis, offering orthogonal functional handles for downstream derivatization. The carboxylic acid and nitro groups enable direct coupling reactions and reductive transformations, while the phenolic hydroxyl supports metal-catalyzed cross-couplings and protection strategies. Its bench-stable crystalline form facilitates handling and purification in synthetic workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: