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Ethyl 4-(4-fluorophenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate

  • CAS No. 5937-24-6

  • Cat. No. CS-0312976
  • Purity≥97%
  • MDL No.MFCD00500223

*For research and further manufacturing use only, not for direct human use.

Ethyl 4-(4-fluorophenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate|CS-0312976

Structure of 5937-24-6

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General Information

  • CAS No. 5937-24-6
  • Cat. No. CS-0312976
  • Purity ≥97%
  • MDL No. MFCD00500223
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₁₅FN₂O₃
  • Molecular Weight 278.28
  • Synonym(s) 4-(4-fluorophenyl)-5-(ethoxycarbonyl)-6-methyl-3,4-dihydropyrimidin-2(1H)-one
  • SMILES CCOC(C1=C(NC(NC1C2=CC=C(F)C=C2)=O)C)=O

Synthesis

  • Route1

    References

    • Dhumaskar, Kashinath L.; Meena, Surya Nandan; Ghadi, Sanjeev C.; Tilve, Santosh G. Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 13 p. 2897 - 2899
  • Route2

    References

    • Khosropour, Ahmad R.; Khodaei, Mohammd M.; Beygzadch, Mojtaba; Jokar, Mahbubeh Heterocycles, 2005 , vol. 65, # 4 p. 767 - 773
  • Route3

    References

    • Khodaei, Mohammad Mehdi; Khosropour, Ahmad Reza; Jowkar, Mahbubeh Synthesis, 2005 , # 8 art. no. Z21704SS, p. 1301 - 1304

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301
Precautionary Statements : P264-P270-P330-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   67.43
  • LogP   2.0167
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   3

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