Lot numbers can be found on the outside label of a product:
2,5-Dichloroquinoline
-
CAS No. 59412-12-3
- Cat. No. CS-W006927
- Purity≥95%
- MDL No.MFCD00832074
*For research and further manufacturing use only, not for direct human use.
Structure of 59412-12-3
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 59412-12-3
- Cat. No. CS-W006927
- Purity ≥95%
- MDL No. MFCD00832074
- Storage Store at room temperature
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₉H₅Cl₂N
- Molecular Weight 198.05
- Synonym(s) DICHLOROQUINOLINE(2,5-)
- SMILES ClC1=C2C=CC(Cl)=NC2=CC=C1
Description
2,5-Dichloroquinoline is a heterocyclic compound featuring two chlorine substituents at the 2- and 5-positions of the quinoline core. This electron-deficient scaffold serves as a key building block in medicinal chemistry and materials science. The dichloro substitution enhances reactivity in cross-coupling transformations while maintaining thermal stability under standard conditions. Its rigid, planar structure supports π-conjugation in optoelectronic applications.
Application
2,5-Dichloroquinoline serves as a versatile building block in medicinal chemistry and materials science, enabling palladium-catalyzed cross-coupling reactions due to its well-established reactivity at the C2 and C5 positions. The electron-deficient quinoline core enhances stability and facilitates functionalization under mild conditions. Its dual chloro substituents offer orthogonal reactivity for sequential transformations, making it ideal for constructing complex heterocyclic scaffolds with predictable regiochemistry.
Synthesis
-
Route1
-
90224-97-8 - ~%
-
In-stock
59412-12-3
References
-
Karramkam, Mylene; Dolle, Frederic; Valette, Heric; Besret, Laurent; Bramoulle, Yann; Hinnen, Francoise; Vaufrey, Francoise; Franklin, Carine; Bourg, Sebastien; Coulon, Christine; Ottaviani, Michele; Delaforge, Marcel; Loc'h, Christian; Bottlaender, Michel; Crouzel, Christian Bioorganic and medicinal chemistry, 2002 , vol. 10, # 8 p. 2611 - 2623
-
-
Route2
-
23981-22-8 - ~91%
-
In-stock
59412-12-3
References
-
Li, Jian-Sen; Chen, Fa-Xian; Shikiya, Ronald; Marky, Luis A.; Gold, Barry Journal of the American Chemical Society, 2005 , vol. 127, # 36 p. 12657 - 12665
-
-
Route3
-
In-stock
611-34-7 - ~%
-
In-stock
59412-12-3
References
-
Karramkam, Mylene; Dolle, Frederic; Valette, Heric; Besret, Laurent; Bramoulle, Yann; Hinnen, Francoise; Vaufrey, Francoise; Franklin, Carine; Bourg, Sebastien; Coulon, Christine; Ottaviani, Michele; Delaforge, Marcel; Loc'h, Christian; Bottlaender, Michel; Crouzel, Christian Bioorganic and medicinal chemistry, 2002 , vol. 10, # 8 p. 2611 - 2623
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302-H315-H319-H335
|
|
|
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 12.89
- LogP 3.5416
- H_Acceptors 1
- H_Donors 0
- Rotatable_Bonds 0
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- 2,5-Dichloroquinoline sigma2,5-Dichloroquinoline manufacturer2,5-Dichloroquinoline price2,5-Dichloroquinoline structure2,5-Dichloroquinoline SDSbuy 2,5-Dichloroquinoline2,5-Dichloroquinoline supplier2,5-Dichloroquinoline uses2,5-Dichloroquinoline molecular weightprice of 2,5-Dichloroquinoline2,5-Dichloroquinoline chemical name formula of 2,5-Dichloroquinoline