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CS-W001157 4
Total: USD 88.00

2-Amino-2-methylbutanoic acid

  • CAS No. 595-39-1

  • Cat. No. CS-0311817
  • Purity≥98%
  • MDL No.MFCD00272968
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2-Amino-2-methylbutanoic acid|CS-0311817

Structure of 595-39-1

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Description

2-Amino-2-methylbutanoic acid is a sterically hindered α-amino acid featuring a branched alkyl side chain. This structural motif enhances metabolic stability and influences conformational preferences in peptide design. The molecule integrates readily into synthetic peptides, serving as a key residue for probing steric effects in enzyme-substrate interactions.

Application

2-Amino-2-methylbutanoic acid serves as a valuable chiral building block in peptide synthesis and medicinal chemistry, offering a sterically hindered α-amino acid scaffold with enhanced metabolic stability. Its side chain supports diverse functionalization and participates reliably in standard coupling reactions, facilitating the construction of bioactive peptidomimetics and heterocyclic frameworks. The compound exhibits good bench stability and is compatible with common protecting group strategies.

General Information

  • CAS No. 595-39-1
  • Cat. No. CS-0311817
  • Purity ≥98%
  • MDL No. MFCD00272968
  • Storage RT, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₁NO₂
  • Molecular Weight 117.15
  • Synonym(s) Isovaline
  • SMILES NC(C(O)=O)(CC)C

Computational Chemistry Data

  • TPSA   63.32
  • LogP   0.1984
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   2

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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