Lot numbers can be found on the outside label of a product:
3,4-Dihydroquinoxalin-2(1H)-one
-
CAS No. 59564-59-9
- Cat. No. CS-0046843
- Purity≥95%
- MDL No.None
*For research and further manufacturing use only, not for direct human use.
Structure of 59564-59-9
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 59564-59-9
- Cat. No. CS-0046843
- Purity ≥95%
- MDL No. None
- Storage 4°C, protect from light
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₈H₈N₂O
- Molecular Weight 148.16
- Synonym(s) 3,4-Dihydroquinoxalin-2-ol
- SMILES O=C1NC2=C(NC1)C=CC=C2
Description
3,4-Dihydroquinoxalin-2(1H)-one features a saturated quinoxaline core with a lactam functionality, offering enhanced solubility and stability compared to fully aromatic analogs. This scaffold integrates readily into medicinal chemistry libraries, serving as a key heterocyclic motif for kinase inhibitors and CNS-targeted therapeutics.
Application
3,4-Dihydroquinoxalin-2(1H)-one serves as a versatile scaffold in medicinal chemistry, enabling efficient construction of quinoxaline-based heterocycles. Its bench-stable nature and compatibility with diverse functional groups facilitate straightforward derivatization via standard coupling and cyclization protocols. Functions as a key building block for bioactive molecules, particularly in kinase inhibitor and antimicrobial agent development.
Synthesis
-
Route1
-
105-36-2 -
95-54-5
- ~80%
-
In-stock
59564-59-9
References
-
Qiao, Jennifer X.; Wang, Tammy C.; Ruel, Rejean; Thibeault, Carl; L'Heureux, Alexandre; Schumacher, William A.; Spronk, Steven A.; Hiebert, Sheldon; Bouthillier, Gilles; Lloyd, John; Pi, Zulan; Schnur, Dora M.; Abell, Lynn M.; Hua, Ji; Price, Laura A.; Liu, Eddie; Wu, Qimin; Steinbacher, Thomas E.; Bostwick, Jeffrey S.; Chang, Ming; Zheng, Joanna; Gao, Qi; Ma, Baoqing; McDonnell, Patricia A.; Huang, Christine S.; Rehfuss, Robert; Wexler, Ruth R.; Lam, Patrick Y. S. Journal of Medicinal Chemistry, 2013 , vol. 56, # 22 p. 9275 - 9295
-
-
Route2
-
389065-48-9 - ~80%
-
In-stock
59564-59-9
References
-
Smil, David V.; Manku, Sukhdev; Chantigny, Yves A.; Leit, Silvana; Wahhab, Amal; Yan, Theresa P.; Fournel, Marielle; Maroun, Christiane; Li, Zuomei; Lemieux, Anne-Marie; Nicolescu, Alina; Rahil, Jubrail; Lefebvre, Sylvain; Panetta, Anthony; Besterman, Jeffrey M.; Deziel, Robert Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 3 p. 688 - 692
-
-
Route3
-
![Ethyl 2-[(2-nitrophenyl)amino]acetate|CS-0209782](https://file.chemscene.com/productPIC/CS-0209782.gif)
5428-05-7 - ~90%
-
In-stock
59564-59-9
References
-
TenBrink, Ruth E.; Im, Wha B.; Sethy, Vimala H.; Tang, Andrew H.; Carter, Don B. Journal of Medicinal Chemistry, 1994 , vol. 37, # 6 p. 758 - 768
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302-H315-H319-H335
|
|
|
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 41.13
- LogP 1.0506
- H_Acceptors 2
- H_Donors 2
- Rotatable_Bonds 0
Similar Products
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- 3,4-Dihydroquinoxalin-2(1H)-one sigma3,4-Dihydroquinoxalin-2(1H)-one manufacturer3,4-Dihydroquinoxalin-2(1H)-one price3,4-Dihydroquinoxalin-2(1H)-one structure3,4-Dihydroquinoxalin-2(1H)-one SDSbuy 3,4-Dihydroquinoxalin-2(1H)-one3,4-Dihydroquinoxalin-2(1H)-one supplier3,4-Dihydroquinoxalin-2(1H)-one uses3,4-Dihydroquinoxalin-2(1H)-one molecular weightprice of 3,4-Dihydroquinoxalin-2(1H)-one3,4-Dihydroquinoxalin-2(1H)-one chemical name formula of 3,4-Dihydroquinoxalin-2(1H)-one