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Structure of 59611-52-8
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6-Fluoro-1,2,3,4-tetrahydroquinoline features a fluorinated heterocyclic core that enhances metabolic stability and modulates electronic properties. This bench-stable scaffold integrates readily into medicinal chemistry libraries, offering improved membrane permeability and targeted binding affinity in bioactive molecule design.
6-Fluoro-1,2,3,4-tetrahydroquinoline serves as a valuable scaffold in medicinal chemistry, offering enhanced metabolic stability and modulated lipophilicity. Its fluorinated aromatic core enables favorable binding interactions in target proteins, while the saturated ring facilitates downstream functionalization via standard electrophilic substitution or transition-metal-catalyzed coupling reactions. The compound exhibits good bench stability and compatibility with common protecting group strategies, making it a practical building block for the synthesis of bioactive heterocycles and API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: