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CS-W001157 4
Total: USD 88.00

Ethyl 4-(hydroxymethyl)picolinate

  • CAS No. 59663-96-6

  • Cat. No. CS-0151671
  • Purity≥97%
  • MDL No.MFCD09844039
  • HazMat Fee +

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Ethyl 4-(hydroxymethyl)picolinate|CS-0151671

Structure of 59663-96-6

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Description

Ethyl 4-(hydroxymethyl)picolinate features a hydroxymethyl group at the 4-position of the picolinate ring, enabling direct functionalization in synthetic transformations. This bench-stable ester integrates readily into medicinal chemistry workflows, offering a handle for derivatization while maintaining solubility and compatibility with common reaction conditions.

Application

Ethyl 4-(hydroxymethyl)picolinate serves as a versatile building block in medicinal chemistry, enabling straightforward derivatization of the pyridine core. The hydroxymethyl group facilitates oxidation to the carboxylic acid, reductive alkylation, or ether formation, while the ester functionality supports selective transformations. Its bench-stable nature and compatibility with standard coupling and protection protocols make it well-suited for iterative synthesis workflows targeting heterocyclic scaffolds and API intermediates.

General Information

  • CAS No. 59663-96-6
  • Cat. No. CS-0151671
  • Purity ≥97%
  • MDL No. MFCD09844039
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₁NO₃
  • Molecular Weight 181.19
  • Synonym(s) ethyl 4-(hydroxyMethyl)picolite
  • SMILES CCOC(=O)C1=NC=CC(=C1)CO

Computational Chemistry Data

  • TPSA   59.42
  • LogP   0.7506
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   3

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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