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Structure of 59663-96-6
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Ethyl 4-(hydroxymethyl)picolinate features a hydroxymethyl group at the 4-position of the picolinate ring, enabling direct functionalization in synthetic transformations. This bench-stable ester integrates readily into medicinal chemistry workflows, offering a handle for derivatization while maintaining solubility and compatibility with common reaction conditions.
Ethyl 4-(hydroxymethyl)picolinate serves as a versatile building block in medicinal chemistry, enabling straightforward derivatization of the pyridine core. The hydroxymethyl group facilitates oxidation to the carboxylic acid, reductive alkylation, or ether formation, while the ester functionality supports selective transformations. Its bench-stable nature and compatibility with standard coupling and protection protocols make it well-suited for iterative synthesis workflows targeting heterocyclic scaffolds and API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: