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CS-W001157 4
Total: USD 88.00

Triethylsilanol

  • CAS No. 597-52-4

  • Cat. No. CS-0153892
  • Molecule weight132.28
  • Purity≥98%
  • MDL No.MFCD00042640

*For research and further manufacturing use only, not for direct human use.

Triethylsilanol|CS-0153892

Structure of 597-52-4

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General Information

  • CAS No. 597-52-4
  • Cat. No. CS-0153892
  • Purity ≥98%
  • MDL No. MFCD00042640
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₆OSi
  • Molecular Weight 132.28
  • Synonym(s) Triethyl(hydroxy)silane
  • SMILES CC[Si](CC)(CC)O

Description

Triethylsilanol offers a robust, bench-stable platform for silanol-based transformations. This moisture-tolerant reagent integrates readily into synthetic sequences requiring controlled silicon functionality. Its triethyl substitution enhances solubility in organic media while maintaining reactivity toward nucleophilic substitution and condensation pathways.

Application

Triethylsilanol serves as a stable, bench-friendly silane source for direct C–H silylation and hydrosilylation reactions. Its moderate reactivity enables selective functionalization of complex substrates under mild conditions, with excellent compatibility across diverse functional groups. The product facilitates efficient access to silyl-protected intermediates and is well-suited for scalable synthesis workflows.

Synthesis

  • Route1
    • null|null
      617-86-7
    • ~96%
    • In-stock
      Triethylsilanol|CS-0153892
      597-52-4

    References

    • Liu, Ting; Yang, Fan; Li, Yongfeng; Ren, Liang; Zhang, Liqiang; Xu, Kai; Wang, Xian; Xu, Chunming; Gao, Jinsen Journal of Materials Chemistry A, 2014 , vol. 2, # 1 p. 245 - 250
  • Route2
    • null|null
      994-30-9
    • ~95%
    • In-stock
      Triethylsilanol|CS-0153892
      597-52-4

    References

    • Gmelin Handbook: Si: MVol.C, 85, page 233 - 235
  • Route3
    • null|null
      617-86-7
    • (4-Bromophenyl)(3-fluoro-4-methylphenyl)methanol|CS-0717482
      853348-88-6
    • ~0%
    • null|null
      853348-89-7
    • In-stock
      Triethylsilanol|CS-0153892
      597-52-4

    References

    • GLAXO GROUP LIMITED Patent: WO2005/51397 A1, 2005 ; Location in patent: Page/Page column 21 ; WO 2005/051397 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS02
Signal Word : Warning
UN#: 1987
Class : 3
Packing Group : Ⅲ
Hazard Statements : H226
Precautionary Statements : P210-P233-P240-P241-P242-P243-P280-P370+P378-P501

Quality Control

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Computational Chemistry Data

  • TPSA   20.23
  • LogP   1.9839
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   3

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