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CS-W001157 4
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Methyl 3-methylpicolinate

  • CAS No. 59718-84-2

  • Cat. No. CS-W008502
  • Molecule weight151.16
  • Purity≥98%
  • MDL No.MFCD03789583

*For research and further manufacturing use only, not for direct human use.

Methyl 3-methylpicolinate|CS-W008502

Structure of 59718-84-2

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General Information

  • CAS No. 59718-84-2
  • Cat. No. CS-W008502
  • Purity ≥98%
  • MDL No. MFCD03789583
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₉NO₂
  • Molecular Weight 151.16
  • Synonym(s) Methyl 3-methylpyridine-2-carboxylate
  • SMILES COC(=O)C1=NC=CC=C1C

Description

Phosphodiesterase inhibitor

Application

Methyl 3-methylpicolinate serves as a versatile building block in synthetic organic chemistry, enabling efficient construction of pyridine-based scaffolds. Its ester functionality facilitates selective transformations, while the methyl-substituted pyridine ring provides enhanced stability and compatibility with standard coupling and functionalization protocols. The compound exhibits excellent bench stability and simplifies purification, making it well-suited for iterative synthesis in medicinal chemistry and process development workflows.

Synthesis

  • Route1
    • null|null
      67-56-1
    • In-stock
      3-Methylpicolinic acid|CS-W002499
      4021-07-2
    • ~85%
    • In-stock
      Methyl 3-methylpicolinate|CS-W008502
      59718-84-2

    References

    • Yaremenko, Anatoliy G.; Volochnyuk, Dmitriy M.; Shelyakin, Vyacheslav V.; Grygorenko, Oleksandr O. Tetrahedron, 2013 , vol. 69, # 33 p. 6799 - 6803
  • Route2
    • null|null
      594-27-4
    • null|null
      157865-84-4
    • ~51%
    • In-stock
      Methyl 3-methylpicolinate|CS-W008502
      59718-84-2

    References

    • Subramanyam, Chakrapani; Chattarjee, Sankar; Mallamo, John P. Tetrahedron Letters, 1996 , vol. 37, # 4 p. 459 - 462
  • Route3
    • null|null
      67-56-1
    • null|null
      1071068-55-7
    • ~%
    • In-stock
      Methyl 3-methylpicolinate|CS-W008502
      59718-84-2

    References

    • Journal of Organic Chemistry, , vol. 63, # 22 p. 7840 - 7850

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   39.19
  • LogP   1.17662
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   1

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