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CS-W001157 4
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tert-Butyl (1-(3-bromophenyl)cyclopropyl)carbamate

  • CAS No. 597563-17-2

  • Cat. No. CS-0102092
  • Purity≥95%
  • MDL No.MFCD19381711

*For research and further manufacturing use only, not for direct human use.

tert-Butyl (1-(3-bromophenyl)cyclopropyl)carbamate|CS-0102092

Structure of 597563-17-2

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General Information

  • CAS No. 597563-17-2
  • Cat. No. CS-0102092
  • Purity ≥95%
  • MDL No. MFCD19381711
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₁₈BrNO₂
  • Molecular Weight 312.20
  • Synonym(s) tert-Butyl N-[1-(3-bromophenyl)cyclopropyl]carbamate
  • SMILES O=C(OC(C)(C)C)NC1(C2=CC=CC(Br)=C2)CC1

Description

tert-Butyl (1-(3-bromophenyl)cyclopropyl)carbamate features a cyclopropyl scaffold bearing a brominated phenyl group and a robust tert-butoxycarbonyl protecting group. This stable, moisture-tolerant reagent integrates readily into synthetic sequences requiring controlled introduction of functionalized cyclopropyl units.

Application

tert-Butyl (1-(3-bromophenyl)cyclopropyl)carbamate serves as a stable, bench-ready building block for the synthesis of bioactive cyclopropyl-containing scaffolds. The carbamate group enables reliable N-protection during iterative coupling reactions, while the ortho-brominated phenyl moiety facilitates subsequent palladium-catalyzed cross-couplings. Its compatibility with standard reaction conditions and ease of purification make it a practical choice for medicinal chemistry and process development workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P302+P352-P304+P340

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Computational Chemistry Data

  • TPSA   38.33
  • LogP   3.9629
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

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