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Structure of 598-09-4
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2-(Chloromethyl)-2-methyloxirane is a strained epoxide featuring a reactive chloromethyl group, enabling selective functionalization in synthetic workflows. This bifunctional scaffold integrates seamlessly into complex molecular architectures, offering high chemoselectivity under mild conditions. The molecule exhibits enhanced stability compared to standard halogenated epoxides, facilitating handling and storage without significant decomposition.
2-(Chloromethyl)-2-methyloxirane serves as a versatile bifunctional building block, enabling efficient ring-opening reactions with nucleophiles under mild conditions. Its strained oxirane ring exhibits high reactivity toward amines, thiols, and carboxylates, while the pendant chloromethyl group permits further functionalization via SN2 displacement. This dual functionality facilitates the synthesis of complex heterocycles and side-chain elaborations in medicinal chemistry workflows. The compound demonstrates good bench stability and is amenable to standard purification protocols.
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GHS No : GHS02,GHS05
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Signal Word : Danger
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UN#: 2920
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Class : 8,3
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Packing Group : Ⅱ
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Hazard Statements : H225-H314
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Precautionary Statements : P210-P233-P240-P241-P242-P243-P260-P264-P280-P301+P330+P331-P304+P340-P363-P370+P378-P405-P501
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Lot numbers can be found on the outside label of a product: