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CS-W001157 4
Total: USD 88.00

2-chloroacrylic acid

  • CAS No. 598-79-8

  • Cat. No. CS-0187884
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-chloroacrylic acid|CS-0187884

Structure of 598-79-8

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General Information

  • CAS No. 598-79-8
  • Cat. No. CS-0187884
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃H₃ClO₂
  • Molecular Weight 106.51
  • Synonym(s) ALPHA-CHLOROACRYLIC ACID
  • SMILES C=C(C(=O)O)Cl

Description

2-Chloroacrylic acid features a conjugated system with a strongly electron-withdrawing chlorine substituent, enhancing reactivity in Michael additions and polymerization. This bench-stable compound integrates readily into synthetic routes requiring α,β-unsaturated electrophiles, offering high functional group tolerance and predictable regiochemistry under standard conditions.

Application

2-Chloroacrylic acid serves as a versatile building block in synthetic organic chemistry, enabling efficient access to α,β-unsaturated systems through conjugate addition and Michael-type reactions. Its reactive vinyl functionality facilitates incorporation into heterocyclic scaffolds and functionalized polymers. The molecule exhibits sufficient bench stability for routine handling and is compatible with common protecting group strategies, making it well-suited for iterative synthesis workflows in medicinal chemistry and materials development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3261
Class : 8
Packing Group : Ⅱ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501

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Computational Chemistry Data

  • TPSA   37.3
  • LogP   0.8235
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

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