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CS-W001157 4
Total: USD 88.00

2,4,6-Trimethylphenylboronic acid

  • CAS No. 5980-97-2

  • Cat. No. CS-W016097
  • Molecule weight164.01
  • Purity≥98%
  • MDL No.MFCD00236060

*For research and further manufacturing use only, not for direct human use.

2,4,6-Trimethylphenylboronic acid|CS-W016097

Structure of 5980-97-2

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General Information

  • CAS No. 5980-97-2
  • Cat. No. CS-W016097
  • Purity ≥98%
  • MDL No. MFCD00236060
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₃BO₂
  • Molecular Weight 164.01
  • Synonym(s) 2-Mesityleneboronic Acid
  • SMILES OB(C1=C(C)C=C(C)C=C1C)O

Application

2,4,6-Trimethylphenylboronic acid serves as a stable, bench-ready arylboronic acid that facilitates Suzuki-Miyaura cross-coupling reactions with high functional group tolerance. Its sterically hindered trialkylphenyl framework enhances oxidative stability and simplifies purification, enabling efficient construction of complex biaryl scaffolds in medicinal chemistry and materials synthesis.

Synthesis

  • Route1

    References

    • Leermann, Timo; Leroux, Frederic R.; Colobert, Francoise Organic Letters, 2011 , vol. 13, # 17 p. 4479 - 4481
  • Route2
    • null|null
      121-43-7
    • null|null
      7732-18-5
    • null|null
      2633-66-1
    • ~71%
    • In-stock
      2,4,6-Trimethylphenylboronic acid|CS-W016097
      5980-97-2

    References

    • Gmelin Handbook: B: B-Verb.13, 4.7.2.7, page 226 - 237
  • Route3
    • null|null
      121-43-7
    • ~33%
    • In-stock
      2,4,6-Trimethylphenylboronic acid|CS-W016097
      5980-97-2

    References

    • Brown, Paul; Mahon, Mary F.; Molloy, Kieran C. Journal of the Chemical Society, Dalton Transactions: Inorganic Chemistry (1972-1999), 1992 , # 24 p. 3503 - 3510

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   40.46
  • LogP   0.29166
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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