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Structure of 59817-32-2
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3-(Piperazin-1-yl)phenol features a phenolic hydroxyl group flanked by a piperazine ring, delivering enhanced solubility and tunable basicity. This combination enables effective integration into bioactive scaffolds, where the electron-rich piperazine moiety supports hydrogen bonding and metal coordination. The molecule exhibits bench-stable handling under standard conditions and serves as a key building block in medicinal chemistry.
3-(Piperazin-1-yl)phenol serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through standard coupling and cyclization protocols. Its phenolic hydroxyl group facilitates direct functionalization or protection, while the piperazine moiety offers hydrogen-bonding capacity and metabolic stability. The compound exhibits good bench stability and solubility, simplifying purification and integration into multi-step syntheses.
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GHS Pictogram :
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GHS No : GHS05,GHS06
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Signal Word : Danger
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UN#: 2923
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Class : 8,6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H315-H318-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: