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CS-W001157 4
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3-(Piperidin-4-yl)-1H-indole hydrochloride

  • CAS No. 60155-63-7

  • Cat. No. CS-0548242
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

3-(Piperidin-4-yl)-1H-indole hydrochloride|CS-0548242

Structure of 60155-63-7

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General Information

  • CAS No. 60155-63-7
  • Cat. No. CS-0548242
  • Purity ≥98%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₇ClN₂
  • Molecular Weight 236.74
  • Synonym(s) 4-(3-INDOLE) PIPERIDINE HYDROCHLORIDE
  • SMILES C1CNCCC1C2=CNC3=CC=CC=C32.Cl

Synthesis

  • Route1
    • tert-Butyl 4-(1H-indol-3-yl)piperidine-1-carboxylate|CS-W001455
      155302-28-6
    • ~99%
    • 3-(Piperidin-4-yl)-1H-indole hydrochloride|CS-0548242
      60155-63-7

    References

    • KATHOLIEKE UNIVERSITEIT LEUVEN, K.U. LEUVEN Randamp;;D; reMYND; GRIFFIOEN, Gerard; VAN DOOREN, Tom; ROJAS DE LA PARRA, Veronica; MARCHAND, Arnaud; ALLASIA, Sara; KILONDA, Amuri; CHALTIN, Patrick Patent: WO2010/142801 A1, 2010 ; Location in patent: Page/Page column 201 ; WO 2010/142801 A1
  • Route2
    • 3-(1,2,3,6-Tetrahydropyridin-4-yl)-1H-indole|CS-0071464
      65347-55-9
    • ~69%
    • 3-(Piperidin-4-yl)-1H-indole hydrochloride|CS-0548242
      60155-63-7

    References

    • Conway, Richard J.; Valant, Celine; Christopoulos, Arthur; Robertson, Alan D.; Capuano, Ben; Crosby, Ian T. Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 7 p. 2560 - 2564
  • Route3
    • Indole, ≥99%|CS-1268948
      120-72-9
    • ~%
    • 3-(Piperidin-4-yl)-1H-indole hydrochloride|CS-0548242
      60155-63-7

    References

    • Yang, Shyh-Ming; Tang, Yuting; Zhang, Rui; Lu, Huajun; Kuo, Gee-Hong; Gaul, Michael D.; Li, Yaxin; Ho, George; Conway, James G.; Liang, Yin; Lenhard, James M.; Demarest, Keith T.; Murray, William V. Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 24 p. 6773 - 6776

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   27.82
  • LogP   3.0567
  • H_Acceptors   1
  • H_Donors   2
  • Rotatable_Bonds   1

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