Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

3-Methoxythiophene-2-carboxylic acid

  • CAS No. 60166-83-8

  • Cat. No. CS-0150618
  • Molecule weightNone
  • Purity≥97%
  • MDL No.MFCD01316613

*For research and further manufacturing use only, not for direct human use.

3-Methoxythiophene-2-carboxylic acid|CS-0150618

Structure of 60166-83-8

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 60166-83-8
  • Cat. No. CS-0150618
  • Purity ≥97%
  • MDL No. MFCD01316613
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₆O₃S
  • Molecular Weight None
  • Synonym(s) 2-Carboxy-3-methoxythiophene
  • SMILES COC1=C(C(=O)O)SC=C1

Description

3-Methoxythiophene-2-carboxylic acid features a thiophene core functionalized with a methoxy group at the 3-position and a carboxylic acid at the 2-position, delivering enhanced solubility and electronic modulation. This combination enables direct incorporation into conjugated systems, streamlining synthesis of bioactive heterocycles and materials for organic electronics.

Application

3-Methoxythiophene-2-carboxylic acid serves as a versatile building block in heterocyclic synthesis, enabling efficient access to substituted thiophene scaffolds relevant to medicinal chemistry and materials science. Its carboxylic acid functionality facilitates direct amidation, esterification, and coupling reactions, while the methoxy group provides moderate electron-donating character and orthogonal reactivity. The compound exhibits good bench stability and is compatible with standard purification methods, making it well-suited for iterative synthetic workflows and API precursor development.

Synthesis

  • Route1

    References

    • Chao, Jianhua; Taveras, Arthur G.; Aki, Cynthia J. Tetrahedron Letters, 2009 , vol. 50, # 35 p. 5005 - 5008
  • Route2
    • In-stock
      Methyl 3-hydroxythiophene-2-carboxylate|CS-M0427
      5118-06-9
    • null|null
      74-88-4
    • ~32%
    • In-stock
      3-Methoxythiophene-2-carboxylic acid|CS-0150618
      60166-83-8

    References

    • California Institute of Technology Patent: US7452730 B2, 2008 ;
  • Route3
    • In-stock
      Methyl 3-hydroxythiophene-2-carboxylate|CS-M0427
      5118-06-9
    • null|null
      77-78-1
    • ~%
    • In-stock
      3-Methoxythiophene-2-carboxylic acid|CS-0150618
      60166-83-8

    References

    • Arkiv foer Kemi, , vol. 12, p. 239,243

Safety Information

Download SDS
GHS Pictogram : N/A
GHS No : N/A
Signal Word : N/A
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   46.53
  • LogP   1.4549
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 3-Methoxythiophene-2-carboxylic acid sigma3-Methoxythiophene-2-carboxylic acid manufacturer3-Methoxythiophene-2-carboxylic acid price3-Methoxythiophene-2-carboxylic acid structure3-Methoxythiophene-2-carboxylic acid SDSbuy 3-Methoxythiophene-2-carboxylic acid3-Methoxythiophene-2-carboxylic acid supplier3-Methoxythiophene-2-carboxylic acid uses3-Methoxythiophene-2-carboxylic acid molecular weightprice of 3-Methoxythiophene-2-carboxylic acid3-Methoxythiophene-2-carboxylic acid chemical name formula of 3-Methoxythiophene-2-carboxylic acid
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label