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Structure of 603-71-4
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1,3,5-Trimethyl-2-nitrobenzene features a nitro group flanked by three methyl substituents in a symmetric arrangement, delivering enhanced stability and reduced reactivity compared to less substituted analogs. This electron-deficient aromatic core integrates readily into synthetic pathways requiring controlled electrophilic character, particularly in the development of functionalized intermediates for pharmaceutical and materials applications.
1,3,5-Trimethyl-2-nitrobenzene serves as a valuable synthetic intermediate in aromatic nitration and coupling workflows. Its electron-donating methyl groups enhance reactivity at the para-position relative to the nitro group, enabling selective functionalization. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for use in multistep synthesis of heterocyclic scaffolds and pharmaceutical intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H312-H315-H319-H332-H335
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Precautionary Statements : P260-P261-P264-P270-P271-P280-P301+P310-P302+P352-P304+P340-P304+P341-P305+P351+P338-P312-P330-P332+P313-P337+P313-P362+P364-P363-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: