7-Bromothieno[3,2-b]pyridine

Name: 7-Bromothieno[3,2-b]pyridine
Brand: ChemScene
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CAS No. 603305-89-1
Cat. No. CS-0071705
Molecule weight214.08
Purity≥98%
MDL No.None

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
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Structure of 603305-89-1

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General Information

CAS No. 603305-89-1
Cat. No. CS-0071705
Purity ≥98%
MDL No. None
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₄BrNS
Molecular Weight 214.08
Synonym(s) 7-BroMo-thieno[3,2-b]pyridine
SMILES BrC1=C2SC=CC2=NC=C1

Description

7-Bromothieno[3,2-b]pyridine features a fused thienopyridine core with a bromine substituent at the 7-position, enabling direct functionalization in cross-coupling reactions. This electron-deficient heterocycle integrates readily into pharmaceutical and materials architectures, offering enhanced stability and predictable reactivity under standard conditions.

Application

7-Bromothieno[3,2-b]pyridine serves as a versatile building block in the synthesis of biologically active heterocycles and functional materials. Its bromine substituent enables facile palladium-catalyzed cross-coupling reactions, facilitating the construction of complex molecular architectures. The fused thienopyridine core offers enhanced planarity and electron-rich character, contributing to favorable π-stacking and redox properties. This compound exhibits excellent bench stability and compatibility with standard synthetic protocols, making it a reliable reagent for medicinal chemistry and materials science applications.

Synthesis

Route1
- 69627-02-7
- ~90%
- In-stock
  
  603305-89-1
References
- ELI LILLY AND COMPANY Patent: WO2003/76442 A1, 2003 ; Location in patent: Page/Page column 60 ; WO 03/076442 A1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

TPSA 12.89
LogP 3.0588
H_Acceptors 2
H_Donors 0
Rotatable_Bonds 0

Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Building Blocks Skeleton Aromatic heterocycle compounds Thiophene compounds

Key Words

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7-Bromothieno[3,2-b]pyridine

CAS No. 603305-89-1

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