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CS-W001157 4
Total: USD 88.00

1-Methylquinazoline-2,4(1H,3H)-dione

  • CAS No. 604-50-2

  • Cat. No. CS-0151121
  • Purity≥98%
  • MDL No.MFCD00731030
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

1-Methylquinazoline-2,4(1H,3H)-dione|CS-0151121

Structure of 604-50-2

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Description

1-Methylquinazoline-2,4(1H,3H)-dione features a fused heterocyclic core with dual carbonyl groups and a methyl substituent at the 1-position, conferring enhanced stability and solubility in polar solvents. This scaffold serves as a key building block in medicinal chemistry for kinase inhibitor development and bioactive compound synthesis.

Application

1-Methylquinazoline-2,4(1H,3H)-dione serves as a versatile scaffold in medicinal chemistry, enabling efficient construction of bioactive heterocycles. Its inherent stability and compatibility with diverse functional groups facilitate downstream derivatization via nucleophilic substitution or transition-metal-catalyzed coupling. The molecule functions as a key building block for kinase inhibitors and other pharmaceutical intermediates, offering predictable reactivity and straightforward purification under standard bench conditions.

General Information

  • CAS No. 604-50-2
  • Cat. No. CS-0151121
  • Purity ≥98%
  • MDL No. MFCD00731030
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₈N₂O₂
  • Molecular Weight 176.17
  • Synonym(s) Glycosmicine
  • SMILES CN1C2=CC=CC=C2C(NC1=O)=O

Computational Chemistry Data

  • TPSA   54.86
  • LogP   0.2268
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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