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CS-W001157 4
Total: USD 88.00

5,6,9,10-Tetrahydro-4H,8H-pyrido[3,2,1-ij][1,6]naphthyridine

  • CAS No. 6052-72-8

  • Cat. No. CS-0326883
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

5,6,9,10-Tetrahydro-4H,8H-pyrido[3,2,1-ij][1,6]naphthyridine|CS-0326883

Structure of 6052-72-8

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General Information

  • CAS No. 6052-72-8
  • Cat. No. CS-0326883
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₄N₂
  • Molecular Weight 174.24
  • Synonym(s) 9-Azajulolidine
  • SMILES C1CC2=C3C(=CN=C2)CCCN3C1

Description

This heterocyclic scaffold features a fused pyridine-naphthyridine core with saturated bridge positions, delivering enhanced stability and defined spatial orientation. The rigid, electron-rich framework supports precise molecular positioning in target-directed synthesis. This structural motif enables efficient integration into bioactive small molecules, particularly where controlled conformation and improved metabolic resilience are required.

Synthesis

  • Route1
    • null|null
      107484-81-1
    • ~77%
    • In-stock
      5,6,9,10-Tetrahydro-4H,8H-pyrido[3,2,1-ij][1,6]naphthyridine|CS-0326883
      6052-72-8

    References

    • Wong, Ken-Tsung; Ku, Sung-Yu; Yen, Feng-Wen Tetrahedron Letters, 2007 , vol. 48, # 29 p. 5051 - 5054
  • Route2
    • null|null
      931104-36-8
    • ~84%
    • In-stock
      5,6,9,10-Tetrahydro-4H,8H-pyrido[3,2,1-ij][1,6]naphthyridine|CS-0326883
      6052-72-8

    References

    • Singh, Satwinder; Das, Goutam; Singh, Om V.; Han, Hyunsoo Tetrahedron Letters, 2007 , vol. 48, # 11 p. 1983 - 1986
  • Route3
    • null|null
      504-24-5
    • ~%
    • In-stock
      5,6,9,10-Tetrahydro-4H,8H-pyrido[3,2,1-ij][1,6]naphthyridine|CS-0326883
      6052-72-8

    References

    • Held, Ingmar; Xu, Shangjie; Zipse, Hendrik Synthesis, 2007 , # 8 p. 1185 - 1196

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362+P364

Quality Control

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Computational Chemistry Data

  • TPSA   16.13
  • LogP   1.7804
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

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