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Structure of 60546-62-5
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6-Bromobenzo[d][1,3]dioxole-5-carboxylic acid features a brominated benzodioxole core with a carboxylic acid handle at the 5-position, enabling direct conjugation in cross-coupling reactions. The electron-deficient aryl bromide integrates readily into Suzuki and Negishi transformations, while the ortho-dioxole moiety enhances solubility and stability under standard conditions.
6-Bromobenzo[d][1,3]dioxole-5-carboxylic acid serves as a versatile building block in medicinal chemistry and materials science, enabling direct functionalization at the bromine site via palladium-catalyzed cross-coupling reactions. The carboxylic acid group facilitates derivatization through amide or ester formation, while the 1,3-dioxole ring imparts stability and orthogonality to common protecting group strategies. This compound exhibits excellent bench stability, clean purification profiles, and compatibility with standard synthetic workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: