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Structure of 605644-46-0
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9,9-Dimethyl-2-nitro-9H-fluorene features a rigid, polycyclic fluorene core with a sterically shielded dimethyl substitution at the 9-position, enhancing stability. The para-nitro group imparts strong electron-withdrawing character, enabling participation in cross-coupling reactions and serving as a handle for further functionalization. This compound exhibits excellent bench stability and solubility in common organic solvents, facilitating use in synthetic workflows.
9,9-Dimethyl-2-nitro-9H-fluorene serves as a stable, bench-accessible building block for the synthesis of fluorene-based heterocycles and functionalized aromatic scaffolds. Its nitro group enables selective reduction to an amine, while the sterically protected fluorene core supports diverse coupling reactions and electrophilic transformations. The dimethyl substitution enhances solubility and thermal stability, facilitating purification and scale-up in medicinal chemistry workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: