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tert-Butyl 3-(tosyloxy)azetidine-1-carboxylate

  • CAS No. 605655-08-1

  • Cat. No. CS-0153017
  • Molecule weight327.40
  • Purity≥98%
  • MDL No.MFCD07787192

*For research and further manufacturing use only, not for direct human use.

tert-Butyl 3-(tosyloxy)azetidine-1-carboxylate|CS-0153017

Structure of 605655-08-1

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General Information

  • CAS No. 605655-08-1
  • Cat. No. CS-0153017
  • Purity ≥98%
  • MDL No. MFCD07787192
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₂₁NO₅S
  • Molecular Weight 327.40
  • Synonym(s) tert-butyl 3-{[(4-methylphenyl)sulfonyl]oxy}azetidine-1-carboxylate
  • SMILES CC1=CC=C(C=C1)S(=O)(=O)OC2CN(C2)C(=O)OC(C)(C)C

Synthesis

  • Route1

    References

    • McDonald, Richard I.; Wong, Gene W.; Neupane, Ram P.; Stahl, Shannon S.; Landis, Clark R. Journal of the American Chemical Society, 2010 , vol. 132, # 40 p. 14027 - 14029
  • Route2

    References

    • AMGEN INC.; BREGMAN, Howard; BUCHANAN, John, L.; CHAKKA, Nagasree; DIMAURO, Erin, F.; DU, Bingfan; NGUYEN, Hanh, Nho; ZHENG, Xiao, Mei Patent: WO2011/103196 A1, 2011 ; Location in patent: Page/Page column 101 ; WO 2011/103196 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06,GHS08
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H311-H331-H341
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361+P364-P405-P501

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Computational Chemistry Data

  • TPSA   72.91
  • LogP   2.31962
  • H_Acceptors   5
  • H_Donors   0
  • Rotatable_Bonds   3

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