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CS-W001157 4
Total: USD 88.00

[1,1'-Bi(cyclopropane)]-1-carboxylic acid

  • CAS No. 60629-92-7

  • Cat. No. CS-0053024
  • Purity≥98%
  • MDL No.None
  • HazMat Fee +

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    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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*For research and further manufacturing use only, not for direct human use.

[1,1'-Bi(cyclopropane)]-1-carboxylic acid|CS-0053024

Structure of 60629-92-7

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Description

This cyclopropane-based diacid features a rigid, sterically constrained biaryl scaffold that enhances structural stability and directs regioselective functionalization. The carboxylic acid groups enable efficient conjugation and solubility tuning in polar media, supporting applications in ligand design and molecular scaffold development.

Application

[1,1'-Bi(cyclopropane)]-1-carboxylic acid serves as a robust scaffold for constructing sterically constrained biaryl systems in medicinal chemistry. Its cyclopropyl moieties confer enhanced metabolic stability and rigidity, facilitating precise spatial orientation in target-binding interactions. The carboxylic acid group enables direct derivatization or salt formation, improving solubility and purification. This compound exhibits excellent bench stability and functional group tolerance, making it ideal for iterative synthesis campaigns and library generation.

General Information

  • CAS No. 60629-92-7
  • Cat. No. CS-0053024
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₀O₂
  • Molecular Weight 126.15
  • Synonym(s) 1-cyclopropylcyclopropanecarboxylic acid
  • SMILES OC(=O)C1(CC1)C1CC1

Computational Chemistry Data

  • TPSA   37.3
  • LogP   1.2612
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   2

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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