(2-Bromo-5-chlorophenyl)methanol

Name: (2-Bromo-5-chlorophenyl)methanol
Brand: ChemScene
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CAS No. 60666-70-8
Cat. No. CS-0022371
Purity≥98%
MDL No.MFCD09261147

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
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(2-Bromo-5-chlorophenyl)methanol|CS-0022371

Structure of 60666-70-8

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Description

This bromochlorophenyl methanol features a reactive benzyl alcohol handle flanked by electron-withdrawing halogens, enabling direct functionalization in cross-coupling and nucleophilic substitution reactions. The ortho-bromo and meta-chloro substituents enhance regioselectivity while maintaining bench-stable handling under standard conditions.

Application

(2-Bromo-5-chlorophenyl)methanol serves as a versatile aryl building block in medicinal chemistry and process development, enabling direct functionalization at the benzylic position. Its dual halogenation pattern provides orthogonal reactivity for cross-coupling reactions, while the primary alcohol facilitates derivatization via esterification, ether formation, or oxidation to aldehyde. The compound exhibits good bench stability and is compatible with standard purification techniques, making it suitable for scale-up and multi-step synthesis workflows.

General Information

CAS No. 60666-70-8
Cat. No. CS-0022371
Purity ≥98%
MDL No. MFCD09261147
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₆BrClO
Molecular Weight 221.48
Synonym(s) 2-Bromo-5-chlorobenzyl alcohol
SMILES OCC1=CC(Cl)=CC=C1Br

Computational Chemistry Data

TPSA 20.23
LogP 2.5948
H_Acceptors 1
H_Donors 1
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Functional Group Chloride

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

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(2-Bromo-5-chlorophenyl)methanol

CAS No. 60666-70-8

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