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Structure of 608145-27-3
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2,5-Difluoroterephthalaldehyde features a rigid aromatic core with two fluorine substituents positioned para to the aldehyde groups, enhancing electron-withdrawal and metabolic stability. This configuration supports efficient coupling in transition-metal-catalyzed cross-couplings and enables selective functionalization in pharmaceutical and materials synthesis.
2,5-Difluoroterephthalaldehyde serves as a valuable building block in the synthesis of fluorinated aromatic scaffolds, enabling efficient access to biologically relevant heterocycles and pharmaceutical intermediates. Its dual aldehyde functionalities exhibit high reactivity in condensation reactions, while the ortho-fluoro substituents provide enhanced metabolic stability and modulate electronic properties. The compound demonstrates excellent bench stability and compatibility with standard purification techniques, facilitating seamless integration into multi-step synthetic workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: