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Structure of 609-40-5
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2-Nitrothiophene features a nitro group directly attached to the thiophene ring, creating an electron-deficient heterocycle with enhanced reactivity in transition metal-catalyzed coupling processes. This structural motif enables efficient integration into complex molecular architectures under standard conditions.
2-Nitrothiophene serves as a versatile building block in heterocyclic synthesis, enabling direct functionalization at the C2 position due to the electron-withdrawing nitro group. Its stability under standard reaction conditions and compatibility with cross-coupling protocols facilitate efficient access to substituted thiophenes. The molecule functions as a key intermediate in the construction of bioactive scaffolds and offers predictable reactivity for downstream transformations.
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GHS Pictogram :
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GHS No : GHS07,GHS08
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302+H312+H332-H341
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: