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Structure of 609-70-1
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4-Hydroxynicotinic acid features a strategically positioned hydroxyl group on the pyridine ring, enabling direct functionalization in synthetic routes. This electron-rich moiety enhances reactivity in coupling reactions and supports integration into bioactive scaffolds. The compound exhibits excellent solubility in polar solvents and maintains stability under standard bench conditions, facilitating straightforward handling in process development workflows.
4-Hydroxynicotinic acid serves as a versatile building block in medicinal chemistry, enabling direct incorporation into heterocyclic scaffolds via cyclization or coupling reactions. Its ortho-hydroxyl group facilitates metal chelation and enhances solubility, while the carboxylic acid functions as a key handle for amide bond formation and derivatization. Bench-stable and readily purified by recrystallization, it supports scalable synthesis of bioactive molecules and functionalized pyridine derivatives.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: