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CS-W001157 4
Total: USD 88.00

Boc-D-Cyclopropylglycine

  • CAS No. 609768-49-2

  • Cat. No. CS-W020722
  • Purity≥97%
  • MDL No.MFCD06659124
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Boc-D-Cyclopropylglycine|CS-W020722

Structure of 609768-49-2

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Description

Boc-D-Cyclopropylglycine features a sterically constrained cyclopropyl ring fused to a D-configured glycine backbone, delivering enhanced conformational rigidity. This structural motif enables precise control in peptide synthesis, particularly for incorporating non-canonical amino acids into bioactive sequences. The Boc protecting group ensures stability during coupling steps and facilitates straightforward deprotection under mild acidic conditions.

Application

Boc-D-Cyclopropylglycine serves as a valuable chiral building block for the synthesis of bioactive peptides and peptidomimetics. The cyclopropyl group imparts conformational rigidity, enhancing target binding affinity in medicinal chemistry applications. The Boc protecting group ensures stability during peptide coupling sequences and facilitates straightforward deprotection under mild acidic conditions. This derivative exhibits excellent functional group tolerance and is compatible with standard solid-phase and solution-phase synthesis protocols.

General Information

  • CAS No. 609768-49-2
  • Cat. No. CS-W020722
  • Purity ≥97%
  • MDL No. MFCD06659124
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₇NO₄
  • Molecular Weight 215.25
  • Synonym(s) None
  • SMILES O=C(OC(C)(C)C)N[C@@H](C(O)=O)C1CC1

Computational Chemistry Data

  • TPSA   75.63
  • LogP   1.3743
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   3

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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