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Structure of 610-94-6
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Methyl 2-bromobenzoate is a bench-stable, moisture-tolerant aryl bromide featuring a strategically positioned ester group. This combination enables direct coupling in cross-coupling reactions without requiring additional activation. The ortho-bromo substitution enhances reactivity in palladium-catalyzed processes, while the ester moiety provides a handle for downstream functionalization.
Methyl 2-bromobenzoate serves as a versatile building block in synthetic organic chemistry, enabling palladium-catalyzed cross-coupling reactions such as Suzuki-Miyaura and Stille transformations. The ortho-bromo functionality provides high reactivity in transition metal-mediated processes, while the methyl ester group offers compatibility with standard reduction and functionalization protocols. Its bench-stable nature and ease of purification make it well-suited for multi-step synthesis, particularly in the construction of substituted aromatic scaffolds relevant to medicinal chemistry and materials science.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: