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Structure of 61072-56-8
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4-Chloro-2-fluorobenzaldehyde features a strategically positioned aldehyde group flanked by chlorine and fluorine substituents, enabling selective coupling in cross-coupling reactions. The electron-withdrawing halogens enhance electrophilicity at the carbonyl carbon while maintaining stability under standard conditions. This ortho-halogenated scaffold facilitates direct integration into pharmaceutical intermediates and functionalized aromatic systems.
4-Chloro-2-fluorobenzaldehyde serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient construction of substituted heterocycles and biaryl scaffolds. Its ortho-fluoro and para-chloro substituents provide enhanced reactivity in palladium-catalyzed cross-coupling reactions while maintaining bench stability and compatibility with common protecting group strategies.
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GHS Pictogram :
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GHS No : GHS07,GHS09
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Signal Word : Warning
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UN#: 3077
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Class : 9
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Packing Group : Ⅲ
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Hazard Statements : H315-H319-H411
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Precautionary Statements : P264-P273-P280-P302+P352-P362-P391-P501
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Lot numbers can be found on the outside label of a product: