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CS-W001157 4
Total: USD 88.00

4,4'-Dihydroxybenzophenone

  • CAS No. 611-99-4

  • Cat. No. CS-W014942
  • Molecule weight214.22
  • Purity≥98%
  • MDL No.MFCD00002358

*For research and further manufacturing use only, not for direct human use.

4,4'-Dihydroxybenzophenone|CS-W014942

Structure of 611-99-4

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General Information

  • CAS No. 611-99-4
  • Cat. No. CS-W014942
  • Purity ≥98%
  • MDL No. MFCD00002358
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₀O₃
  • Molecular Weight 214.22
  • Synonym(s) None
  • SMILES C2=C(C(C1=CC=C(O)C=C1)=O)C=CC(=C2)O

Description

4,4'-Dihydroxybenzophenone features two hydroxyl groups positioned para to the carbonyl on opposing phenyl rings, conferring enhanced solubility and polarity. This structural motif enables robust hydrogen bonding and facilitates integration into UV-absorbing polymers and photostable formulations. The compound serves as a key scaffold in organic synthesis for designing multifunctional intermediates.

Application

4,4'-Dihydroxybenzophenone serves as a versatile building block in synthetic organic chemistry, enabling efficient access to polyhydroxylated aromatic systems. Its dual phenolic functionalities facilitate electrophilic substitution, oxidative coupling, and metal-catalyzed cross-coupling reactions. The compound exhibits excellent bench stability and ease of purification, making it well-suited for the construction of advanced heterocyclic scaffolds and functionalized aryl frameworks in medicinal chemistry and materials science applications.

Synthesis

  • Route1

    References

    • Magano, Javier; Chen, Michael H.; Clark, Jerry D.; Nussbaumer, Thomas Journal of Organic Chemistry, 2006 , vol. 71, # 18 p. 7103 - 7105
  • Route2
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      56-23-5
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      108-95-2
    • ~%
    • In-stock
      4,4'-Dihydroxybenzophenone|CS-W014942
      611-99-4

    References

    • Journal of the American Chemical Society, , vol. 47, p. 209
  • Route3
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      124678-79-1
    • ~49%
    • In-stock
      4,4'-Dihydroxybenzophenone|CS-W014942
      611-99-4

    References

    • Spurg, Anke; Waldvogel, Siegfried R. European Journal of Organic Chemistry, 2008 , # 2 p. 337 - 342

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H317-H319-H335
Precautionary Statements : P261-P264-P271-P272-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   57.53
  • LogP   2.3288
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   2

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