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CS-W001157 4
Total: USD 88.00

1-(Piperidin-4-yl)tetrahydropyrimidin-2(1h)-one

  • CAS No. 61220-36-8

  • Cat. No. CS-0349583
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

1-(Piperidin-4-yl)tetrahydropyrimidin-2(1h)-one|CS-0349583

Structure of 61220-36-8

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General Information

  • CAS No. 61220-36-8
  • Cat. No. CS-0349583
  • Purity ≥98%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₇N₃O
  • Molecular Weight 183.25
  • Synonym(s) None
  • SMILES O=C1NCCCN1C2CCNCC2

Synthesis

  • Route1
    • 1-(1-Benzylpiperidin-4-yl)tetrahydropyrimidin-2(1H)-one|CS-0697371
      61220-38-0
    • ~96%
    • 1-(Piperidin-4-yl)tetrahydropyrimidin-2(1h)-one|CS-0349583
      61220-36-8

    References

    • SCHERING CORPORATION Patent: EP1144402 B1, 2004 ; Location in patent: Page 28; 31 ; EP 1144402 B1
  • Route2
    • null|null
      164519-21-5
    • ~97%
    • 1-(Piperidin-4-yl)tetrahydropyrimidin-2(1h)-one|CS-0349583
      61220-36-8

    References

    • Fujimoto, Takuya; Imaeda, Yasuhiro; Konishi, Noriko; Hiroe, Katsuhiko; Kawamura, Masaki; Textor, Garret P.; Aertgeerts, Kathleen; Kubo, Keiji Journal of Medicinal Chemistry, 2010 , vol. 53, # 9 p. 3517 - 3531
  • Route3

    References

    • Zeneca Limited Patent: US5889024 A1, 1999 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   44.37
  • LogP   0.1537
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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