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Structure of 6127-18-0
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4-Bromo-2-methyl-1H-indole is a brominated indole derivative featuring a methyl group at the 2-position and a bromine atom at the 4-position, offering enhanced electron density and reactivity. This bench-stable compound serves as a key building block in medicinal chemistry, enabling efficient access to functionalized heterocycles through cross-coupling and electrophilic substitution reactions.
4-Bromo-2-methyl-1H-indole serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions for C–C bond formation. Its bromine substituent provides high reactivity in Suzuki, Stille, and Negishi couplings, while the methyl group enhances solubility and modulates electronic properties. The indole core offers robust stability under standard reaction conditions, facilitating efficient synthesis of complex heterocyclic scaffolds and pharmaceutical intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: