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Structure of 6134-66-3
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Ethyl 2,2-dichloro-3-oxobutanoate features a sterically hindered α,α-dichloro ketone moiety that enables direct functionalization at the carbonyl center. This bench-stable reagent integrates readily into synthetic sequences requiring electrophilic halogenation or tandem Claisen-type condensations. The dichloro substitution enhances reactivity in nucleophilic addition pathways while maintaining handling ease under standard conditions.
Ethyl 2,2-dichloro-3-oxobutanoate serves as a versatile building block in synthetic organic chemistry, enabling the construction of chlorinated heterocycles and functionalized carbonyl intermediates. Its α,α-dichloro ketone functionality facilitates nucleophilic addition and enolization under mild conditions, while the ester group supports subsequent transformations. The compound exhibits good bench stability and is compatible with standard purification methods, making it valuable for iterative synthesis workflows in medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS02,GHS05
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Signal Word : Danger
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UN#: 2920
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Class : 8 (3)
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Packing Group : Ⅱ
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Hazard Statements : H226-H302-H314-H318-H335-H412
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Precautionary Statements : P210-P273-P280
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Lot numbers can be found on the outside label of a product: