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Structure of 614-27-7
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Methyl 3-oxo-3-phenylpropanoate features a conjugated ketone and ester system flanked by a phenyl group, enabling facile Michael addition and aldol-type cyclizations. This electron-deficient enone scaffold integrates readily into complex heterocycles and serves as a key building block in natural product synthesis and medicinal chemistry.
Methyl 3-oxo-3-phenylpropanoate serves as a versatile building block in synthetic organic chemistry, enabling efficient construction of substituted benzylated heterocycles and functionalized aromatic systems. Its α,β-unsaturated ketone motif facilitates Michael additions, aldol condensations, and transition-metal-catalyzed couplings. The ester group provides a handle for selective reduction or hydrolysis, while the phenyl substituent enhances stability and aids purification. This compound functions reliably in multistep syntheses requiring orthogonal reactivity and bench-stable intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: