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Structure of 61453-48-3
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Ethyl 5-(hydroxymethyl)-1H-pyrazole-3-carboxylate features a pyrazole core with orthogonal functional handles: a hydroxymethyl group enabling downstream derivatization and an ester for selective reduction or hydrolysis. This bench-stable scaffold integrates seamlessly into medicinal chemistry libraries, offering access to diverse heterocyclic architectures through controlled transformations.
Ethyl 5-(hydroxymethyl)-1H-pyrazole-3-carboxylate serves as a versatile building block in medicinal and synthetic chemistry, enabling straightforward functionalization at the C5 hydroxymethyl position. The molecule combines a pyrazole core with orthogonal reactivity—ideal for oxidation to aldehyde or carboxylic acid, ester manipulation, and coupling reactions. Its bench-stable nature and compatibility with standard protection/deprotection sequences make it well-suited for multi-step synthesis of heterocyclic scaffolds and API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: