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CS-W001157 4
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5,6,7,8-Tetrahydro-naphthalene-2-sulfonyl chloride

  • CAS No. 61551-49-3

  • Cat. No. CS-0071625
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

5,6,7,8-Tetrahydro-naphthalene-2-sulfonyl chloride|CS-0071625

Structure of 61551-49-3

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General Information

  • CAS No. 61551-49-3
  • Cat. No. CS-0071625
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₁ClO₂S
  • Molecular Weight 230.71
  • Synonym(s) 5,6,7,8-Tetrahydronaphthalene-2-sulfonyl chloride
  • SMILES O=S(C1=CC=C2CCCCC2=C1)(Cl)=O

Description

5,6,7,8-Tetrahydro-naphthalene-2-sulfonyl chloride features a fully saturated naphthalene core with a sulfonyl chloride group at the 2-position, offering high reactivity for amine coupling. This bench-stable derivative enables efficient synthesis of sulfonamide-linked architectures in medicinal chemistry and materials science applications.

Application

5,6,7,8-Tetrahydro-naphthalene-2-sulfonyl chloride serves as a versatile sulfonyl chloride building block for the synthesis of sulfonamide derivatives. Its fused bicyclic structure provides enhanced stability and predictable reactivity in amine substitution reactions, enabling efficient access to functionalized heterocycles. The compound exhibits excellent bench stability and facilitates straightforward purification, making it well-suited for iterative synthetic workflows in medicinal chemistry and process development.

Safety Information

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GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3261
Class : 8
Packing Group : Ⅲ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501

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Computational Chemistry Data

  • TPSA   34.14
  • LogP   2.4929
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

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